Design and experimental validation of the action of small molecule-based inhibitors of the FADD protein
CD95 is one of the best studied members of the death receptor family.Activation of CD95 leads to the induction of the cell death programme, apoptosis, via formation of the death-inducing signaling complex (DISC).FA DD is a key adaptor protein for the formation of the C D95 DISC Crochet Notions and activation of caspase-8 in the receptor complex.FA